Add MS 56164

FLEMING PAPERS. Vol. LIX. 28^{Oct. 1928-6 April 1932.}

ff. i + 90. 276 x 220mm. Front and back hard, black covers of a ring binder, spine is missing. It was advertised as a ‘simplex notebook’.

This notebook has not been split into sections and as the spine has been removed it is difficult to know if the papers are in the correct order. The notebook seems to have originally housed plain paper and this has been supplemented with other pieces of plain and lined paper.

Notebook includes:

1. f. 3. Blood culture ‘Kenna’ and ‘Thompson’; 6 Nov. 1918.

2. f. 5. Untitled drawing of a cell/sample of blood; n.d.

3. ff. 6-10.

i) List of chemicals and figures

ii) Notes on antiseptics in lined tubes – washes of serum and volume of serum and staphylococcus

iii) Emigration and salt on lined tubes, carbolic on lined tubes

iv) Flavine intravenously into a rabbit with slide cells

4. f. 20. Notes on ‘Milly’ bacillus isolated from abscess by L.C [Leonard Colebrook?], includes a description of bacteria grown from it; 4 Sept. 1928.

5. ff. 21-22. Experiments examining the effect of temperature and time of centrifuging on phagocytosis; n.d.

6. f. 29. Notes on Walsh’s sterilisation of milk; 28 Oct. 1926.

7. f. 30. Experiment examining the absorption from air by stock cultures; 19 Jan. 1927.

8. f. 31. Experiment examining bacteriophage for coli, using a sample from a Rothchild wine, includes a description of the bacteria; 28 Jan. 1928.

9. f. 32. Experiment with coli bacteriophage in broth cultures, includes a description of bacteria; 2 Feb. 1927.

10. f. 33. Experiment to see if serum becomes bactericidal to staphylococcus on keeping; n.d.

11. f. 34. Experiment to examine the influence of mixing bugs with blood on bactericidal in staphylococcus. Includes note in green pen; 24 May 1927.

12. f. 35. Comparison of living and dead staphylococcus vaccine immunisation in vitro. Includes note in green pen ‘No difference except possibly dead vaccine’; 1 June 1925.

13. ff. 36-37. Experiments examining effect of atropine on rabbit leucocytes; 15-22 Dec. 1927.

14. f. 38. Experiment with different methods of agglutination; 23 Dec. 1927.

15. f. 39. Experiment examining the effect of temperature on phagocytosis; 30 Dec. 1927.

16. f. 40. Experiment examining the effect of atropine human and rabbit leucocytes; 28 Jan. 1928.

17. f. 41. Influence of sarcina on growth of staphylococcus, includes a diagram; 29 Jan. 1929.

18. f. 42. Notes on staphylococcus toxin from an article by C. H. Killaway, J. M. Burnet and F. E. Williams in Journal of Pathology and Bacteriology 1930, XXXIII p 889.

19. f. 44. Phage. Notes on experimental plague from article by G. Compton in [American Journal Pathology?] 1930 XLV 754, noted a number of conclusions.

20. f. 46. Experiment with bacteriophage to test drug from an Anglo-French Drug Co (Bact intesti-phage); 24 Sept. 1930.

21. f. 47. Experiment with streptococcus subculture into glucose broth from meat cultures that were five years old; 6 Jan. 1930.

22. f. 48. Experiment with mannite fermentations by staphylococcus; 6 Jan. 1930.

23. f. 51. Experiment with lysol in water serum and blood (horse); 1 Jan. 1930.

24. f. 52. Experiment using staphylococcus on CO2; 13 June 1930.

25. f. 54. Notes on a method of staining flagella; n.d.

26. f. 64. Notes on an experiment using Florey’s mucus; 23 Jan 1929.

27. f. 57. Notes on staining blood [films]. From an article by Moschowski. Cent f. Bact 1923 Vol. 90 No 4/2 256. Includes Borax methyl blue, tannin and Red’s red violet.

28. f. 65. Notes on a patient ‘Wix’, with chronic nasal catarrh and chronic rheumatism; 17 April 1919.

29. ff. 68-70. Notes on patients and their illnesses; 14-21 April 1929.

30. f. 71. Experiment with Eidenhows antiseptic, including slide cells and emigration; 10 May 1929.

31. f. 72. Experiment with staphylococcus from hands of lab workers planted into mannite broth (L.C. refused). Samples from West, McLean, AF, Jennings and Albert; 21 Sept. 1929.

32. f. 74. Experiment with Walsh’s iodine emulsion (60% iodine 10% olive oil); 25 July 1931.

33. f. 75. Experiment with staphylococcus on parainfluenza, includes a diagram; 9 Sept. 1931.

34. f. 76. Experiment with haemophilic bacilli in normal tonsils and swabs from various individuals; 10 Sept. 1931.

35. ff. 80-81. Experiments with two day old fildes broth cultures of parainfluenza, planted in streaks on agar and boiled blood agar with cross streaks of staphylococcus; 17-18 Sept. 1931.

36. f. 83. Experiments with three malignant cases of endocarditis; 5 Oct.

i) Leucocyte efficiency

ii) Opsonic index staphylococcus

iii) Time of opsonisation of staphylococcus on bench

37. f. 84. Experiment with Squires Pfeiffer’s; 3 Nov.

38. f. 85. Experiment with penicillin on KLB; n.d.

39. f. 87. Experiments with vaginal swabs; 1936.

40. f. 89. Experiment with lysozyme in eggs; n.d.

Links with other notebooks:

56159: Loose link between work on blood culture

56160: Walsh

56166: Wix and McLean

56168: Phage

includes:

• ff. 3, 5, 34 Haematology: Experiments by A. Fleming rel. to blood: 1902-1947, n.d.
• ff. 6-10 Chemical compounds: Experiments by A. Fleming rel. to salt: 1902-1925, n.d.
• ff. 6-10 Scientific method: Experiments by A. Fleming using lined tubes: n.d.
• ff. 6-10 Haematology: Experiments by A. Fleming rel. to emigration: 1925, n.d.
• ff. 6-10 Haematology: Experiments by A. Fleming rel. to serum: 1902-1947, n.d.
• ff. 6-10, 51, 71 Pharmacology antiseptics: Experiments and notes by A. Fleming: 1916-1949, n.d.
• ff. 20, 76, 84 Bacteriology: Experiments, notes and photographs by A. Fleming rel. to bacteria: 1928-1947, n.d.
• ff. 21-22, 39 Cell biology: Experiments by A. Fleming rel. to phagocytosis: 1902-1942.
• f. 30 Physiology: Experiments by A. Fleming rel. to absorption: 1927-1939.
• ff. 31-32, 46 Microbiology: Experiments by A. Fleming rel. to bacteriophage: 1927-1930.
• ff. 33-34 Pharmacology: Experiments and notes by A. Fleming rel. to bactericidal: 1902-1947, n.d.
• ff. 34-35, 41-42, 52, 72, 80-81 Bacteriology: Experiments and notes by A. Fleming rel. to staphylococcus: 1910-1947, n.d.
• f. 35 Immunology: Experiments by A. Fleming rel. to immunisation in vitro: 1924-1925.
• f. 35 Immunology: Experiments and notes by A. Fleming rel. to vaccines: 1902-1948, n.d.
• ff. 36-37, 40 Haematology: Experiments by A. Fleming rel. to leucocytes: 1917-1948, n.d.
• f. 38 Haematology: Experiments by A. Fleming rel. to agglutination: 1902-1936, n.d.
• f. 42 Journal of Pathology and Bacteriology: Notes by A. Fleming from an article by C. H. Killaway, J. M. Burnet and F. E. Williams on staphylococcus toxin: n.d.
• f. 44 Bacteriology: Experiments by A. Fleming rel. to phage: n.d.
• f. 47 Bacteriology: Experiments by A. Fleming rel. to streptococcus: 1921-1944, n.d.
• f. 48 Chemical process: Experiments by A. Fleming rel. to fermentation: 1930.
• f. 57 Chemical process: Experiments by A. Fleming rel. to stain [meotia], 30 October-3 November: 1915, n.d.
• f. 64 Physiology: Experiment by A. Fleming using a sample of Florey's mucus, 23 January: 1929.
• ff. 65, 68-70 Scientific method: Patient notes, including graphs, taken by A. Fleming: 1907-1948, n.d.
• ff. 75, 80-81 Pathology infectious diseases: Notes and experiments by A. Fleming rel. to influenza and parainfluenza: 1918-1931, n.d.
• f. 83 Pathology cardiovascular diseases: Experiments by A. Fleming rel. to endocarditis: n.d.
• f. 85 Microbiology penicillin: Experiments and notes by A. Fleming: 1928-1949, n.d.
• f. 89 Biochemistry: Experiments and notes by A. Fleming rel. to lysozyme: 1921-1948, n.d.