Add MS 56167

FLEMING PAPERS. Vol. LXII. 31 Oct. 1929-8 March 1931.

ff. ii + 84. 277 x 223mm. Ring binder with hard, black cover. It is advertised as a ‘simplex’ notebook.

As the notebook is a ring binder it is difficult to know if the papers are in the correct order. The notebook seems to have originally housed plain paper and this has been supplemented with other pieces of plain and lined paper.

The label on the spine has ‘FLU 1930’ and ‘Inhibition’ written on it.

Notebook includes:

Section one: n.d.

ff. 2-11, 13, 17-32. Lists of samples taken from people and various experiments carried out on them. Results are in the form of:

i) Person, where the sample/s came from and description of bacteria.

ii) Morphology, reaction with agar and staphylococcus, reaction with blood agar and staphylococcus and colony

iii) Person and where the sample was taken from (tonsil, teeth and P. N. [post nasal?]

List of people that samples were taken from:

Downer

Maybury

Wills

Bully

Collings

Clayton

Ivans

Cummings

Clifton

Fisk

O’Grady

Parker

Smith

Parker

Willis

Bulley

Hathorne

Steer

Dugleish

Clyton

D. Smith

Brown

Llewellyn

Section two:

1. f. 35. Experiment examining the resistance of different Pfeiffer’s to penicillin – dilution of penicillin and various samples; n. d.

2. ff. 36-38. Notes on samples taken from experiments using ‘Evans No2’; n.d.

Section three: n.d.

ff. 40-44, 46-47. Lists of samples taken from people and various experiments carried out on them. Results are in the form of:

i) Person

ii) Description of the bacteria

ii) Growth and morphology

List of people sample taken from:

Dan

Peter

Clayden

Deacon

Ben

Section four:

1. f. 45. Renumbering of tooth plates of sample replanted in boiled blood; 6 Feb. 1930.

2. f. 53. Growth of Dan’s ‘flu’ on Ridley’s movie; n.d.

3. f. 56. Resistance of various strains of [haemoglobinophilic] bacteria to penicillin; n.d.

Section five: 31 Oct. 1929-8 March 1931.

ff. 57-70. Various – inhibition, Pfeiffer, penicillin and cats

i) Experiment with penicillin – Plate with half plain agar and half agar/penicillin solution (five dilutions). Incubated and then staphylococcus, streptococcus and diphtheroids planted across whole surface. Results include diagrams.

ii) Diagram of an agar plate with half penicillin agar and half boiled blood agar with staphylococcus streaked across

iii) Experiment involving Fitz ‘Pfeiffer’, includes diagram of results

iv) Experiment examining the inhibition of Pfeiffer by pneumo with ‘student’ nasal mucus – results include diagram of the plate

v) B. prodigiosus action on other bacteria: Staphylococcus aureus, cat, staphylococcus albus, AF saliva and Craddock

vi) ‘Fitz’ pfeiffers

vii) Experiment with AF postnasal (no cold) sample

viii) Fildes medium

ix) List entitled ‘gram negative cocci’ n.d.

a. Weichslebraun, Meningo, 1887, Fort. de Med. V. 573 620.

Meningo, 1902, Centralblatt für Bakteriologie, XZXXIII. 570

Meningo, 1903, Wiener Klinische Wochenschrift, XVIII. 992

b. R. Pfeiffer, Cat, 1896

c. Glon & N. Pfeiffer, Cat, 1902, Zeitschrift für klinische Medizin, XLIV. 262

d. Dunn & Gordon, Cat, 1905 British Medical Journal, II 421

e. Von Lingelshein, Classification, 1906, Klinisches Jahrbuch , XV 373.

f. Kutschen, Classification, 1906, Kohler Wassermann Band IV. 600

g. Elser & Humtoon, Classification, 1909, Journal of Medical Research, XX 371

h. J E Gordon, Classification, 1921, Journal Infectious Disease XXIV, 462

i. S P Wilson, Classification, 1928, Journal of Pathology and Bacteriology, XXXI 477

j. G S Wilson & M.M. Smith, Classification, 1928, Journal of Pathology and Bacteriology, XXXI 597

k. Martin, Classification, 1911, Journal of Bacteriology and Pathology, XV 76

l. Gaskell, Classification, 1916 Medical Research Council Special Report Series, No 2

m. Dunham, Classification, 1906, Journal of Infectious Diseases, Supplement, 2 p10

n. Atkin Colour, Meningo, 1923, British Journal of Experimental Pathology, IV 325

x) Experiment examining inhibition by pneumo, notes include a diagram

Section six: 24^{Jan. 1931.}

f. 71. Flu

i) Work on influenza bacteriology, tested with an epidemic of influenza. Symptoms includes two day fever with pain, with little on sore throat or chest trouble

ii) Patients: Bell, Slade, Giles, Dunbar, Williams, Morgan

iii) Notes include number of days they have had it, results of film and description of the culture

Section four: n.d.

f. 73. B. Influenza – Rough and Smooth

No notes just blank pages

Section seven: n.d.

f. 84.

i) Notes on an unidentified article by I. Winchell and E. G. Stillman, in Journal of Experimental Medicine 1919 XXX, 497 and 257. The notes and figures seem to be related to tonsils and the pharynx

ii) Percentages taken from:

Scott (Bible)

1920 70%

1925 50%

Topley and Wilson

1925 Oct. 77%

1926 May 43%

1927 March 80%

1927 May 60%

Link with other notebooks:

56162: Penicillin (in particular Pfeiffer’s)

56168: Inhibition

includes:

• ff. 2-11, 13, 17-32, 36-38, 40-47 Scientific method: Analysis of samples from patients taken by A, Fleming, some of which include a description of their complaints: 1929-1944, n.d.
• ff. 35, 57-70 Microbiology penicillin: Experiments and notes by A. Fleming: 1928-1949, n.d.
• ff. 53, 71, 73 Pathology infectious diseases: Notes and experiments by A. Fleming rel. to influenza and parainfluenza: 1918-1931, n.d.
• f. 56 Haematology: Experiments by A. Fleming rel. to blood: 1902-1947, n.d.
• ff. 56-70 Bacteriology: Experiments, notes and photographs by A. Fleming rel. to bacteria: 1928-1947, n.d.
• ff. 57-70 Chemical process: Experiments by A. Fleming rel. to inhibition: 1917-1942.
• f. 69 Biology: Notes by A. Fleming on classification from various articles: n.d.
• f. 84 Journal of Experimental Medicine: Notes by A. Fleming on the tonsil and pharynx from an article by I. Winchell and E. G. Stillman: n.d.