Name
- Smith, Thomas, Captain; of the Imperial Fleet1
- Soderini, Francesco, Cardinal, 1453-15241
- Sommai, Margerita, née Medici; wife of B Sommai1
- Sommaia, Ridolfo, ward of Balì R de' Medici1
- Spagni, Pietro Maria, Chancellor of the Grand Duke of Tuscany1
- Spannocchi, Silvio1
- Spighi, Zanobi, priest1
- Spinelli, Family1
- Spini, Geri1
- Spinola, Ambrosio, 1st Marqués de Los Balbases1
- Spinola, Francesco1
- Stefano, Alessandro, of Montevarchi; alias 'Guercio', fl 15721
- Strozzi, Federigo di Roberto1
- Suárez, Gómez, 3rd Duke of Feria, Spanish nobleman, 1587-16341
- Sylos, Francesco, Knight of St John of Jerusalem1
- Tamburacci, Orazio Maria1
- Tanciani, Pietro, of Arezzo; advocate1
- Tieri, Family1
- Todeschi, Guglielmo1
- Toledo Osorio, Pedro Alvarez, Marqués de Villafranca, Governor of Milan 1616-16181