Name
- Segneri, Paolo, Jesuit preacher1
- Sera, Alfonso del1
- Sera, Cosimo del, Principal Minister of the Magona in Tuscany1
- Serra, Anna, wife of F Serra1
- Serragli, Giuliano1
- Serristori, Antonio, Florentine senator1
- Simonelli, Tommaso, Vicario ad Causas in Arezzo1
- Smith, Thomas, Captain; of the Imperial Fleet1
- Soderini, Francesco, Cardinal, 1453-15241
- Sommai, Margerita, née Medici; wife of B Sommai1
- Sommaia, Ridolfo, ward of Balì R de' Medici1
- Spagni, Pietro Maria, Chancellor of the Grand Duke of Tuscany1
- Spannocchi, Silvio1
- Spighi, Zanobi, priest1
- Spinelli, Family1
- Spini, Geri1
- Spinola, Ambrosio, 1st Marqués de Los Balbases1
- Spinola, Francesco1
- Stefano, Alessandro, of Montevarchi; alias 'Guercio', fl 15721
- Strozzi, Federigo di Roberto1